DMT (N,N-Dimethyltryptamine) is a hallucinogenic tryptamine drug that occurs naturally in many plants and animals. It is also referred to as the “spirit molecule” due to the intense psychedelic experience.Although lesser known than other psychedelics such as LSD or magic mushrooms, DMT produces a brief but intense visual and auditory hallucinogenic experience.
DMT is a Schedule I controlled substance in the United States; this means that it is illegal to manufacture, buy, possess, or distribute the drug. The substance has a high potential for abuse, no recognized medical use, and a lack of accepted safety parameters for the use of the drug.
DMT has no approved medical use in the United States. but can be used by researchers under a Schedule I research registration that requires approval from both the Drug Enforcement Administration (DEA) and the Food and Drug Administration (FDA).
Despite its illegal status, DMT is used in some religious ceremonies and various settings for an “awakening” or to obtain deep spiritual insight.
DMT is a white crystalline powder that is derived from certain plants found in Mexico, South America, and parts of Asia, such as Psychotria viridis and Banisteriopsis caapi.
It is typically consumed in the following ways:
vaporized or smoked in a pipe
consumed orally in brews like ayahuasca
snorted or injected on rare occasions
The chemical root structure of DMT is similar to the anti-migraine drug sumatriptan, and it acts as a non-selective agonist at most or all of the serotonin receptors, particularly at the serotonin 5-ht2a receptor. Serotonin is a neurotransmitter that has a large effect on the majority of our brain cells.